Sarah, setting the bias when you change the power tubes is a very good idea on a fixed bias amp, which this amp is. It should be checked and set even when using graded tubes such as the Groove Tubes mentioned, but these will usually be closer than run of the mill tubes bought elsewhere, though you have to know your starting point (i.w. where the tubes are biased now) and you also pay more for graded tubes like that.
Setting the bias can also be very dangerous if you don't know what you are doing because the amp is live and running with the chassis opened when you set the bias. You could pick up a Weber Bias Rite
https://taweber.powweb.com/biasrite/br_page.htm which helps greatly to set the bias. He makes meters that check the plate voltage and the cathode current so all you need is to take those numbers and do the calculation (which I could explain later if you wanted to know) but you still have to open the chassis in a live amp to adjust the bias voltage, and you need an insulated screwdriver to do this, preferably completely plastic.
If you know what you are doing or take the time to learn, then setting the bias in an amp is very simple and safe as long as some safety precautions are followed. I was just doing this to an amp project in the garage and have lived to tell about it, so it can be done.

Of course I've also spent many years reading and learning about amps, and quite a few years working on them too, so I'm a bit ahead of most people. Still, it isn't hard. If you want to learn, I and others can help you.
Greg